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These include multiple myeloma and colorectal, pancreatic, ovarian, endometrial and postmenopausal breast cancers

GLP1s in higher amounts also act on portions of the brain that suppress appetite and signal satiety (feeling full)

These strategies remain entirely preclinical, with ongoing efforts focused on mechanistic validation and delivery feasibility

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What are glucagon-like peptide-1 (GLP-1) receptor agonists

6 Emerging clinical applications 6.1 Non-alcoholic steatohepatitis (NASH)/non-alcoholic fatty liver disease (NAFLD) Studies investigating GLP-1 receptor agonists for the prevention of NAFLD/NASH indicate potential effectiveness via several molecular mechanisms